From a financial standpoint, boxes make the most sense if you have a larger collection. A 5K box runs about $5. Placing 5000 cards into 9 pocket pages would take 556 pages, assuming you didn't double up on the pockets!!! Even if you did, that is still 278 pages. I think a box of 100 pages run about $15-20, so you are talking about $100+ per 5000 cards stored.
I'd love to have everything in albums, but that would cost me a fortune. My other problem is I am always moving things around. Binders are best for sets and such, where items are in a set order that never changes. You can leave an opening for missing cards in sheets, but if you have cards sorted differently, you may need to move them around if you add or subtract.
I prefer 5K boxes for bulk and super shoes for toploader and sleeved cards. I then use shoeboxes for the oddball and small boxed sets and such.