Not sure I understand what you're asking. Are you trying to flip the box, are you looking to trade the contents of the box after you open it? If it's the first, you'd have to buy and hold until they were sold out. Why would I buy a $110 box from you if I could get it myself for $90 elsewhere? If you hold them for a year or two and the supply dries up a bit, someone may well take the gamble at a profit to you hoping for a big hit.
If it's the second option, then it depends on what you pull. Personally I rate them as some of the least attractive cards ever produced. I'd rather have an index card. That said, pulling stuff like a Joe Nathan, Juan Francisco, and a triple of Tyler Flowers, John Danks, and Brent Lillibridge probably isn't going to get you close to even.