In keeping with what Tony said, I too was at the 09 Fanfest. Surprisingly good given how many people were there, it was a lot of fun too.
Rollie Fingers gave away pre-signed items and had a photo op during this time, but did not sign memorabilia. I know he signs for a living now, so that might be part of it, but his line moved very fast, so that may be helpful as well.
My advice? Go! It was a lot of fun, and there were a lot of other things to do when not waiting in line. Good idea that just for cards had to split up as well, that will maximize your ability to get through lines, or get items signed.
One more piece of advice: make a graphing board before you go. People use folders or I have often just used a piece of cardboard with photo corners to hold cards down. This way you are not shuffling through cards, toploaders, cases, etc. to get your item ready. Or wear cargo shorts if you are carrying baseballs, that way you dont have to mess with your backpack too much in line.
God Bless, have a lot of fun!
Kevin Mc
***GET A SEATING CHART!! The ushers all have these, or should. If you come across an usher that doesnt, keep asking. These are essential, as they tell you who is sitting where, and when! This way you can plan your route through the event and maximize your signers!